Justin Roiland once again does a lot of the legwork
High on Life is a veritable smorgasbord of cartoon and video game voice acting. As is customary, since this is a Justin Roiland production, he’s going to be doing a lot of voices: but at this point he has a lot of friends and connections, so the entire cast is stacked as well. Here’s a list of everyone who plays core roles in the games, as well as some minor appearances/cameos.
Principal cast (the guns/knife, in the order you acquire them – plus your mentor, Gene, and your sister, Lizzie
- Kenny: Justin Roiland
- Knifey: Michael Cusack
- Sweezy: Betsy Sodaro
- Gus: JB Smoove
- Creature: Tim Robinson
- Gene: Dave Herman
- Lizzie: Laura Silverman
Additional cast
Note that a few of these appearances are very short, to the point where they’re mostly cameos. Several appear in scenes that last 30 seconds or less. In terms of the cast itself, Roiland is also linked directly to Thomas Middleditch and Mary Mack: who play Terry and Jesse respectively alongside of Roiland in the TV show Solar Opposites.
- Dave Herman
- Jennifer Hale
- Joel Haver
- Kevin McDonald
- Maria Bamford
- Mary Mack
- Mike Stoklasa
- Nolan North
- Tara Strong
- Thomas Middleditch